Dorsal hindbrain ablation results in rerouting of neural crest migration and changes in gene expression, but normal hyoid development.

@article{Saldivar1997DorsalHA,
  title={Dorsal hindbrain ablation results in rerouting of neural crest migration and changes in gene expression, but normal hyoid development.},
  author={Jose Saldivar and John W Sechrist and Catherine Ellen Krull and Seth Ruffins and Marianne Bronner-Fraser},
  journal={Development},
  year={1997},
  volume={124 14},
  pages={2729-39}
}
Our previous studies have shown that hindbrain neural tube cells can regulate to form neural crest cells for a limited time after neural fold removal (Scherson, T., Serbedzija, G., Fraser, S. E. and Bronner-Fraser, M. (1993). Development 188, 1049-1061; Sechrist, J., Nieto, M. A., Zamanian, R. T. and Bronner-Fraser, M. (1995). Development 121, 4103-4115). In the present study, we ablated the dorsal hindbrain at later stages to examine possible alterations in migratory behavior and/or gene… CONTINUE READING