Dorsal determinants in the Xenopus egg are firmly associated with the vegetal cortex and behave like activators of the Wnt pathway.

@article{Marikawa1997DorsalDI,
  title={Dorsal determinants in the Xenopus egg are firmly associated with the vegetal cortex and behave like activators of the Wnt pathway.},
  author={Yusuke Marikawa and Yuheng Li and Richard P. Elinson},
  journal={Developmental biology},
  year={1997},
  volume={191 1},
  pages={
          69-79
        }
}
The Xenopus egg contains maternal dorsal determinants that are specifically located at the vegetal cortex. To study physical and functional properties of the dorsal determinants, we took advantage of the animal-vegetal reversed embryo. The animal-vegetal reversed embryo is produced by inversion of the fertilized egg, which results in formation of ectoderm and endoderm from the unpigmented and the pigmented halves, respectively [Neff et al. (1983). Dev. Biol. 97, 103-112; Black and Gerhart (1985… CONTINUE READING

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