Doppler-ultrasound as a predictor of uterine fibroid response to GnRH therapy.

  title={Doppler-ultrasound as a predictor of uterine fibroid response to GnRH therapy.},
  author={N Kanelopoulos and Spiros Dendrinos and Anastasia Oikonomou and Periklis Panagopoulos and Vyron Markussis},
  journal={International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics},
  volume={82 1},
OBJECTIVES GnRH agonists (GnRHa) are able to reduce the bleeding and size of fibroids. We monitored the response of fibroids to GnRHa with power-Doppler ultrasound. METHODS Thirty-five women with fibroids, aged 32-48, received a 6-month course with the GnRHa triptorelin (Decapeptyl, Ipsen, France). The resistance index (RI) of the uterine artery was measured with power-Doppler ultrasound. RESULTS The uterine volume reduced from 470+/-347 to 297+/-295 cm3 (P<0.01) at the 6th month of… CONTINUE READING