Doping Control Analysis of Metamfepramone and Two Major Metabolites Using Liquid Chromatography-Tandem Mass Spectrometry

@article{Thevis2009DopingCA,
  title={Doping Control Analysis of Metamfepramone and Two Major Metabolites Using Liquid Chromatography-Tandem Mass Spectrometry},
  author={Mario Thevis and Gerd Sigmund and Andreas Thomas and Vassilios Gougoulidis and Grigory M Rodchenkov and Wilhelm Schänzer},
  journal={European Journal of Mass Spectrometry},
  year={2009},
  volume={15},
  pages={507 - 515}
}
The sympathomimetic agent metamfepramone (2-dimethylamino-1-phenylpropan-1-one, dimethylpropion) is widely used for the treatment of the common cold or hypotonic conditions. Due to its stimulating properties and its rapid metabolism resulting in major degradation products such as methylpseudoephedrine and methcathinone, it has been considered relevant for doping controls by the World Anti-Doping Agency (WADA). The rapid degradation of the active drug complicates the detection of metamfepramone… 

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