Dopaminergic receptor agents and the basal ganglia: Pharmacological properties and interactions with the GABA-ergic system

@article{Timmerman1993DopaminergicRA,
  title={Dopaminergic receptor agents and the basal ganglia: Pharmacological properties and interactions with the GABA-ergic system},
  author={W. Timmerman},
  journal={Pharmacy World and Science},
  year={1993},
  volume={15},
  pages={90-92}
}
In the present series of studies, attention was focussed particularly on dopaminergic D2 receptor compounds, with emphasis on the enantiomers of the potent and selective dopamine D2 receptor agonist N-0437. Drugs that display activity at D2 receptors are of great interest as potentially new therapeutic agents for the treatments of Parkinson’s disease and schizophrenia. With these therapeutic uses in mind, the pharmacological profiles of the enantiomers of N-0437 were considered. The… CONTINUE READING