Dopaminergic neuronal survival and the effects of bFGF in explant, three dimensional and monolayer cultures of embryonic rat ventral mesencephalon

Abstract

Embryonic substantia nigra cells when transplanted into the striatum can reverse many of the defects of Parkinson's disease. The efficacy of such grafts is compromised by the poor survival of grafted dopaminergic neurones; typically, 3–10% survive transplantation. We used three tissue culture models to identify stages in the procedure for the preparation… (More)
DOI: 10.1007/BF00241123

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@article{Fawcett1995DopaminergicNS, title={Dopaminergic neuronal survival and the effects of bFGF in explant, three dimensional and monolayer cultures of embryonic rat ventral mesencephalon}, author={James W. Fawcett and Roger A. Barker and Stephen B. Dunnett}, journal={Experimental Brain Research}, year={1995}, volume={106}, pages={275-282} }