Dopaminergic mechanisms of individual differences in human effort-based decision-making.

@article{Treadway2012DopaminergicMO,
  title={Dopaminergic mechanisms of individual differences in human effort-based decision-making.},
  author={Michael Tilghman Treadway and Joshua W. Buckholtz and Ronald L. Cowan and Neil D. Woodward and Rui Li and M. Sib Ansari and Ronald M. Baldwin and Ashley N. Schwartzman and Robert M. Kessler and David H. Zald},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2012},
  volume={32 18},
  pages={
          6170-6
        }
}
Preferences for different combinations of costs and benefits are a key source of variability in economic decision-making. However, the neurochemical basis of individual differences in these preferences is poorly understood. Studies in both animals and humans have demonstrated that direct manipulation of the neurotransmitter dopamine (DA) significantly impacts cost/benefit decision-making, but less is known about how naturally occurring variation in DA systems may relate to individual… CONTINUE READING

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