Dopaminergic influences on the P300 abnormality in Parkinson's disease.

  title={Dopaminergic influences on the P300 abnormality in Parkinson's disease.},
  author={Young Ho Sohn and Gyung Whan Kim and K Huh and Jong Sung Kim},
  journal={Journal of the neurological sciences},
  volume={158 1},
This study was designed to evaluate the contribution of central dopaminergic mechanisms to the P300 event-related potential (P300) abnormality in Parkinson's disease. We measured the P300 in 37 non-demented patients with Parkinson's disease (19 de novo and 18 levodopa-treated) and 15 age-matched healthy volunteers. The P300 measurement was repeated in 14 de novo patients, after 6-12 months levodopa therapy. The severity of parkinsonian symptom was assessed using the UPDRS-motor scale. De novo… CONTINUE READING

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