Corpus ID: 38523809

Dopaminergic activity of a nonhydroxylated aminotetralin derivative (TL-68) on cat hearts.

@article{Ilhan1984DopaminergicAO,
  title={Dopaminergic activity of a nonhydroxylated aminotetralin derivative (TL-68) on cat hearts.},
  author={M. Ilhan and J. Long and J. Cannon},
  journal={Archives internationales de pharmacodynamie et de therapie},
  year={1984},
  volume={271 2},
  pages={
          213-9
        }
}
  • M. Ilhan, J. Long, J. Cannon
  • Published 1984
  • Biology, Medicine
  • Archives internationales de pharmacodynamie et de therapie
  • An aminotetralin derivative, N,N-dipropyl-2-amino-1,2,3,4 tetrahydronaphtelene (TL-68) produced dose- and concentration-dependent inhibition of heart rate increases induced by stimulation of the cardioaccelerator nerves of anesthetized cats and by transmural stimulation of isolated cat right atria. These inhibitions were reversed by the dopaminergic antagonist haloperidol and not by the alpha2 adrenergic antagonist yohimbine. Results suggest that TL-68-induced inhibition of heart rate responses… CONTINUE READING
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