Dopaminergic Modulation of Effort-Related Choice Behavior as Assessed by a Progressive Ratio Chow Feeding Choice Task: Pharmacological Studies and the Role of Individual Differences

@inproceedings{Randall2012DopaminergicMO,
  title={Dopaminergic Modulation of Effort-Related Choice Behavior as Assessed by a Progressive Ratio Chow Feeding Choice Task: Pharmacological Studies and the Role of Individual Differences},
  author={Patrick Randall and M. E. Pardo and Eric J. Nunes and Laura L{\'o}pez Cruz and V Kiran Vemuri and Alex Makriyannis and Younis Baqi and Christa E. M{\"u}ller and Merc{\'e} Correa and John D Salamone},
  booktitle={PloS one},
  year={2012}
}
Mesolimbic dopamine (DA) is involved in behavioral activation and effort-related processes. Rats with impaired DA transmission reallocate their instrumental behavior away from food-reinforced tasks with high response requirements, and instead select less effortful food-seeking behaviors. In the present study, the effects of several drug treatments were assessed using a progressive ratio (PROG)/chow feeding concurrent choice task. With this task, rats can lever press on a PROG schedule… CONTINUE READING
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