Dopaminergic Modulation of Effort-Related Choice Behavior as Assessed by a Progressive Ratio Chow Feeding Choice Task: Pharmacological Studies and the Role of Individual Differences

Abstract

Mesolimbic dopamine (DA) is involved in behavioral activation and effort-related processes. Rats with impaired DA transmission reallocate their instrumental behavior away from food-reinforced tasks with high response requirements, and instead select less effortful food-seeking behaviors. In the present study, the effects of several drug treatments were… (More)
DOI: 10.1371/journal.pone.0047934

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@inproceedings{Randall2012DopaminergicMO, title={Dopaminergic Modulation of Effort-Related Choice Behavior as Assessed by a Progressive Ratio Chow Feeding Choice Task: Pharmacological Studies and the Role of Individual Differences}, author={Patrick Randall and Marta Romano Pardo and Eric J. Nunes and Laura L{\'o}pez Cruz and V Kiran Vemuri and Alex Makriyannis and Younis Baqi and Christa E. M{\"{u}ller and Merc{\'e} Correa and John D Salamone}, booktitle={PloS one}, year={2012} }