Dopamine transporter SPECT using fast kinetic ligands: 123I-FP-β-CIT versus 99mTc-TRODAT-1

@article{Laere2004DopamineTS,
  title={Dopamine transporter SPECT using fast kinetic ligands: 123I-FP-β-CIT versus 99mTc-TRODAT-1},
  author={Koen Van Laere and Liesbeth De Ceuninck and Ren{\'e} J. Dom and Jimmy Van den Eynden and Hubert P. Vanbilloen and Jan Cleynhens and Patricia Dupont and Guy Bormans and Alfons Verbruggen and Luc Mortelmans},
  journal={European Journal of Nuclear Medicine and Molecular Imaging},
  year={2004},
  volume={31},
  pages={1119-1127}
}
A comparative study was carried out on two promising presynaptic dopamine transporter single-photon emission tomography (SPECT) radioligands with a fast pharmacokinetic profile, 123I-FP-β-CIT (FP) and 99mTc-TRODAT-1 (TR), in order to assess their differential diagnostic power in early parkinsonism and their sensitivity for detection of disease progression… CONTINUE READING