Dopamine release is heterogeneous within microenvironments of the rat nucleus accumbens.

@article{Wightman2007DopamineRI,
  title={Dopamine release is heterogeneous within microenvironments of the rat nucleus accumbens.},
  author={R Mark Wightman and Michael L Heien and Kate M. Wassum and Leslie A Sombers and Brandon J. Aragona and Amina S Khan and Jennifer L. Ariansen and Joseph F. Cheer and Paul E. M. Phillips and Regina M Carelli},
  journal={The European journal of neuroscience},
  year={2007},
  volume={26 7},
  pages={2046-54}
}
Many individual neurons within the intact brain fire in stochastic patterns that arise from interactions with the neuronal circuits that they comprise. However, the chemical communication that is evoked by these firing patterns has not been characterized because sensors suitable to monitor subsecond chemical events in micron dimensions have only recently become available. Here we employ a voltammetric sensor technology coupled with principal component regression to examine the dynamics of… CONTINUE READING

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