Dopamine release in the dorsal striatum during cocaine-seeking behavior under the control of a drug-associated cue.

@article{Ito2002DopamineRI,
  title={Dopamine release in the dorsal striatum during cocaine-seeking behavior under the control of a drug-associated cue.},
  author={Rutsuko Ito and Jeffrey W. Dalley and Trevor W. Robbins and Barry J. Everitt},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2002},
  volume={22 14},
  pages={6247-53}
}
Compulsive drug use is characterized by a pattern of drug seeking and consumption that becomes progressively habitual and less and less modifiable by external and internal factors. Although traditional views would posit that nigrostriatal dopamine (DA) neurons originating in the substantia nigra and innervating the dorsal striatum are primarily concerned with motor functions, recent studies have implicated the dorsal striatum in mediating stimulus-response (habit) learning. In this study, in… CONTINUE READING
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