Dopamine regulates melanopsin mRNA expression in intrinsically photosensitive retinal ganglion cells

@article{Sakamoto2005DopamineRM,
  title={Dopamine regulates melanopsin mRNA expression in intrinsically photosensitive retinal ganglion cells},
  author={Katsuhiko Sakamoto and Cuimei Liu and Manami Kasamatsu and Nikita V Pozdeyev and P. Michael Iuvone and Gianluca Tosini},
  journal={European Journal of Neuroscience},
  year={2005},
  volume={22}
}
In mammals a subpopulation of retinal ganglion cells are intrinsically photosensitive (ipRGCs), express the photopigment melanopsin, and play an important role in the regulation of the nonimage‐forming visual system. We have recently reported that melanopsin mRNA and protein levels in the rat retina are under photic and circadian control. The aim of the present work was to investigate the mechanisms that control melanopsin expression in the rat retina. We discovered that dopamine (DA) is… 

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...

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  • Biology
    Proceedings of the National Academy of Sciences of the United States of America
  • 2005
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