Dopamine receptors in human lymphocytes: radioligand binding and quantitative RT-PCR assays.

@article{Kirillova2008DopamineRI,
  title={Dopamine receptors in human lymphocytes: radioligand binding and quantitative RT-PCR assays.},
  author={Galina P Kirillova and Rebecca J Hrutkay and Michael R. Shurin and Galina V. Shurin and Irina L. Tourkova and Michael M Vanyukov},
  journal={Journal of neuroscience methods},
  year={2008},
  volume={174 2},
  pages={272-80}
}
Analysis of dopamine receptors (DR) in lymphocytes of the human peripheral blood mononuclear cell (PBMC) fraction is an attractive tool for evaluation of functional properties of dopaminergic function underlying variation in complex psychological/psychopathological traits. Receptor binding assays (RBAs) with selective radioligands, which are widely used in CNS studies, have not produced consistent results when applied to isolated PBMC. We tested the assay conditions that could be essential for… CONTINUE READING