Dopamine receptor binding in inbred mice: strain differences in mesolimbic and nigrostriatal dopamine binding sites.

@article{Bhme1981DopamineRB,
  title={Dopamine receptor binding in inbred mice: strain differences in mesolimbic and nigrostriatal dopamine binding sites.},
  author={Ralf B{\"o}hme and Roland D. Ciaranello},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1981},
  volume={78 5},
  pages={3255-9}
}
Dopamine receptors were examined by Scatchard analysis in the striatal and olfactory tubercle regions of 11 inbred mouse strains. Simultaneous determinations of the binding characteristics of 3H-labeled 2-amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene (ADTN), a dopaminergic agonist, and [3H]spiroperidol, a dopaminergic antagonist, were examined. Among the 11 strains, the equilibrium dissociation constant (Kd) for agonist binding did not vary in either the striatum or the olfactory tubercle… CONTINUE READING

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Biometry: the Principles and Practices of Statistics in Biological Research (Freeman, San Francisco)

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