Dopamine receptor activation promotes adult neurogenesis in an acute Parkinson model.

@article{Winner2009DopamineRA,
  title={Dopamine receptor activation promotes adult neurogenesis in an acute Parkinson model.},
  author={Beate Winner and Paula A. Desplats and Christian Hagl and Jochen Klucken and Robert Aigner and Sonja Ploetz and J{\"o}rn S L{\"a}mke and Alexandra Karl and Ludwig Aigner and Eliezer Masliah and Erich B{\"u}rger and J{\"u}rgen Winkler},
  journal={Experimental neurology},
  year={2009},
  volume={219 2},
  pages={543-52}
}
Cell proliferation of neural progenitors in the subventricular zone (SVZ) of Parkinson disease (PD) patients and animal models is decreased. It was previously demonstrated that the neurotransmitter dopamine modulates cell proliferation in the embryonic brain. The aim of the present study was to analyze whether oral treatment with the dopamine receptor agonist pramipexole (PPX) modulates adult neurogenesis in the SVZ/olfactory bulb system in a dopaminergic lesion model. 6-Hydroxydopamine (6-OHDA… CONTINUE READING

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