Dopamine receptor 2 activation inhibits ovarian vascular endothelial growth factor secretion in vitro: implications for treatment of ovarian hyperstimulation syndrome with dopamine receptor 2 agonists.

@article{Ferrero2014DopamineR2,
  title={Dopamine receptor 2 activation inhibits ovarian vascular endothelial growth factor secretion in vitro: implications for treatment of ovarian hyperstimulation syndrome with dopamine receptor 2 agonists.},
  author={Hortensia Ferrero and Carmen Maria Garc{\'i}a-Pascual and Ra{\'u}l Aguero G{\'o}mez and Francisco Delgado-Rosas and Omar Cauli and Carlos Sim{\'o}n and Francisco X Gayt{\'a}n and Antonio Pellicer},
  journal={Fertility and sterility},
  year={2014},
  volume={101 5},
  pages={1411-8}
}
OBJECTIVE To ascertain whether vascular endothelial growth factor (VEGF) secretion by luteinized granulosa cells (GCs) is modulated by the dopaminergic system in a dose-dependent fashion and how this is related to the differential efficacy of dopamine receptor 2 (D2)-agonists (D2-ag) in preventing ovarian hyperstimulation syndrome (OHSS). DESIGN The… CONTINUE READING