Dopamine neurons make glutamatergic synapses in vitro.

  title={Dopamine neurons make glutamatergic synapses in vitro.},
  author={David Sulzer and Myra P Joyce and Lu Lin and Daron Geldwert and Suzanne N. Haber and Takamichi Hattori and Stephen Rayport},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  volume={18 12},
Interactions between dopamine and glutamate play prominent roles in memory, addiction, and schizophrenia. Several lines of evidence have suggested that the ventral midbrain dopamine neurons that give rise to the major CNS dopaminergic projections may also be glutamatergic. To examine this possibility, we double immunostained ventral midbrain sections from rat and monkey for the dopamine-synthetic enzyme tyrosine hydroxylase and for glutamate; we found that most dopamine neurons immunostained… CONTINUE READING
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