Dopamine modulates use-dependent plasticity of inhibitory synapses.

  title={Dopamine modulates use-dependent plasticity of inhibitory synapses.},
  author={Dinara V. Baimoukhametova and Sarah A. Hewitt and Cheryl A Sank and Jaideep Singh Bains},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  volume={24 22},
The release of the hormones oxytocin (OT) and vasopressin (VP) into the circulation is dictated by the electrical activity of hypothalamic magnocellular neurosecretory cells (MNCs). In the paraventricular nucleus of the hypothalamus (PVN), MNC neuronal activity is exquisitely sensitive to changes in input from inhibitory GABAergic synapses. To explore the hypothesis that efficacy at these synapses is dictated by the rate at which a given synapse is activated, we obtained whole-cell recordings… CONTINUE READING
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