Dopamine modulates the kinetics of ion channels gated by excitatory amino acids in retinal horizontal cells.

@article{Knapp1990DopamineMT,
  title={Dopamine modulates the kinetics of ion channels gated by excitatory amino acids in retinal horizontal cells.},
  author={Andrew G. Knapp and Karl F. Schmidt and John E. Dowling},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1990},
  volume={87 2},
  pages={767-71}
}
Upon exposure to dopamine, cultured teleost retinal horizontal cells become more responsive to the putative photoreceptor neurotransmitter L-glutamate and to its analog kainate. We have recorded unitary and whole-cell currents to determine the mechanism by which dopamine enhances ion channels activated by these agents. In single-channel recordings from cell… CONTINUE READING