Dopamine-induced relaxation of the guinea-pig isolated jejunum is not mediated through dopamine receptors.

@article{Lucchelli1990DopamineinducedRO,
  title={Dopamine-induced relaxation of the guinea-pig isolated jejunum is not mediated through dopamine receptors.},
  author={Adele Lucchelli and Cinzia Boselli and Enzo Grana},
  journal={Pharmacological research},
  year={1990},
  volume={22 4},
  pages={433-44}
}
The possible involvement of specific dopamine receptors in the relaxing effect of dopamine in the guinea-pig isolated jejunum has been investigated. The relaxing effect of dopamine does not show the tachyphylaxis phenomenon and it is present in preparations from guinea-pigs pretreated with reserpine. These results indicate that dopamine has a direct action. Comparison of the effect of dopamine with those of other dopamine receptor agonists, i.e. apomorphine, bromocriptine and the DA1 selective… CONTINUE READING

Similar Papers

Loading similar papers…