Dopamine in manic depressive illness. A pharmacological synthesis.

Abstract

If the clinical symptoms of mania are a consequence of increased activity in central dopaminergic (DA) pathways in predisposed individuals, then drugs increasing DA neurotransmission should precipitate or exacerbate mania in such people, whereas drugs which reduce DA neurotransmission should ameliorate manic symptoms. Of the drugs which enhance DA… (More)

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@article{Silverstone1985DopamineIM, title={Dopamine in manic depressive illness. A pharmacological synthesis.}, author={Trevor Silverstone}, journal={Journal of affective disorders}, year={1985}, volume={8 3}, pages={225-31} }