Dopamine depletion in the rostral nucleus accumbens alters the cerebral metabolic response to cocaine in the rat.

Abstract

The functional consequences of dopamine depletion in the rostral nucleus accumbens were examined using the quantitative 2-[14C]deoxyglucose method for determining rates of local cerebral glucose utilization. Cerebral metabolism was determined in 35 brain structures of Sprague-Dawley rats with unilateral 6-hydroxydopamine or sham lesions of the rostral… (More)

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