Dopamine as the wind of the psychotic fire: new evidence from brain imaging studies.

@article{Laruelle1999DopamineAT,
  title={Dopamine as the wind of the psychotic fire: new evidence from brain imaging studies.},
  author={Marc Laruelle and Anissa Abi-Dargham},
  journal={Journal of psychopharmacology},
  year={1999},
  volume={13 4},
  pages={358-71}
}
Abnormalities of dopamine function in schizophrenia are suggested by the common antidopaminergic properties of antipsychotic medications. However, direct evidence of a hyperdopaminergic state in schizophrenia has been difficult to demonstrate, given the difficulty of measuring dopamine transmission in the living human brain. This situation is rapidly changing. Recent developments in positron emission tomography and single-photon emission tomographic techniques enabled measurement of acute… CONTINUE READING

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