Dopamine and working memory mechanisms in prefrontal cortex.

@article{Surmeier2007DopamineAW,
  title={Dopamine and working memory mechanisms in prefrontal cortex.},
  author={D. James Surmeier},
  journal={The Journal of physiology},
  year={2007},
  volume={581 Pt 3},
  pages={
          885
        }
}
The neural mechanisms underlying working memory – the capacity to manipulate information in short-term memory and use it to guide action – have been the subject of considerable speculation and debate for the last 30 years. The prefrontal cortex (PFC) has been the focus of studies aimed at this question since neurons there were shown to stay active during the delay period in working memory tasks, suggesting that they somehow were involved in the processing of items in memory (Fuster, 1973). In… CONTINUE READING

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