Dopamine and Serotonin Receptor Binding and Antipsychotic Efficacy


The relationship between clinically effective antipsychotic drug dosage and binding affinity to cloned dopamine (DA) and serotonin receptor subtypes was analyzed in an effort to elucidate the contribution of individual receptor subtypes to medication response. Clinically effective dose and binding affinity to D2 DA receptor were modestly correlated for… (More)
DOI: 10.1038/sj.npp.1301305


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