Dopamine and Addiction.

@article{Wise2020DopamineAA,
  title={Dopamine and Addiction.},
  author={Roy A Wise and Mykel A. Robble},
  journal={Annual review of psychology},
  year={2020},
  volume={71},
  pages={
          79-106
        }
}
Addiction is commonly identified with habitual nonmedical self-administration of drugs. It is usually defined by characteristics of intoxication or by characteristics of withdrawal symptoms. Such addictions can also be defined in terms of the brain mechanisms they activate; most addictive drugs cause elevations in extracellular levels of the neurotransmitter dopamine. Animals unable to synthesize or use dopamine lack the conditioned reflexes discussed by Pavlov or the appetitive behavior… 
Dopamine, behavior, and addiction
Addictive drugs are habit-forming. Addiction is a learned behavior; repeated exposure to addictive drugs can stamp in learning. Dopamine-depleted or dopamine-deleted animals have only unlearned
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