Dopamine agonists: structure-activity relationships.

@article{Cannon1985DopamineAS,
  title={Dopamine agonists: structure-activity relationships.},
  author={J. Cannon},
  journal={Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques},
  year={1985},
  volume={29},
  pages={
          303-414
        }
}
  • J. Cannon
  • Published 1985
  • Chemistry, Medicine
  • Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques
In the several years since Blaschko [1] first suggested that dopamine might be a neurotransmitter substance, many chemical compounds have been found to possess dopamine-like actions. This review surveys classes of structures for which putative dopaminergic agonism has been reported, and cites structure-activity correlations. Some aspects of metabolism of the agents are addressed, which seem to have relevance to structure-activity considerations and to strategy of drug design. 
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