Dopamine affects parvalbumin expression during cortical development in vitro.

@article{Porter1999DopamineAP,
  title={Dopamine affects parvalbumin expression during cortical development in vitro.},
  author={Linda L. Porter and Elizete Rizzo and Jean-Pierre Hornung},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={1999},
  volume={19 20},
  pages={8990-9003}
}
This study was undertaken to determine how dopamine influences cortical development. It focused on morphogenesis of GABAergic neurons that contained the calcium-binding protein parvalbumin (PV). Organotypic slices of frontoparietal cortex were taken from neonatal rats, cultured with or without dopamine, harvested daily (4-30 d), and immunostained for parvalbumin. Expression of parvalbumin occurred in the same regional and laminar sequence as in vivo. Expression in cingulate and entorhinal… CONTINUE READING