Dopamine abnormalities in the neocortex of patients with temporal lobe epilepsy.

  title={Dopamine abnormalities in the neocortex of patients with temporal lobe epilepsy.},
  author={Luisa L. Rocha and Mario Alonso-Vanegas and Juana Villeda-Hern{\'a}ndez and Mario M{\'u}jica and J Miguel Cisneros-Franco and Mario L{\'o}pez-G{\'o}mez and Cecilia Zavala-Tecuapetla and Christian Lizette Fr{\'i}as-Soria and Jos{\'e} Segovia-Vila and Anna Borsodi},
  journal={Neurobiology of disease},
  volume={45 1},
Experiments were designed to evaluate different variables of the dopaminergic system in the temporal cortex of surgically treated patients with temporal lobe epilepsy (TLE) associated with mesial sclerosis (MTLE, n=12) or with cerebral tumor or lesion (n=8). In addition, we sought to identify dopaminergic abnormalities in those patients with epilepsy that had comorbid anxiety and depression. Specifically, we investigated changes in dopamine and its metabolites, D1 and D2 receptors, tyrosine… CONTINUE READING
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