Dopamine Receptor Signaling

@article{Neve2004DopamineRS,
  title={Dopamine Receptor Signaling},
  author={Kim A Neve and Jeremy K. Seamans and Heather Trantham-Davidson},
  journal={Journal of Receptors and Signal Transduction},
  year={2004},
  volume={24},
  pages={165 - 205}
}
The D1-like (D1, D5) and D2-like (D2, D3, D4) classes of dopamine receptors each has shared signaling properties that contribute to the definition of the receptor class, although some differences among subtypes within a class have been identified. D1-like receptor signaling is mediated chiefly by the heterotrimeric G proteins Gαs and Gαolf, which cause sequential activation of adenylate cyclase, cylic AMP-dependent protein kinase, and the protein phosphatase-1 inhibitor DARPP-32. The increased… Expand
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