Dopamine D4 receptor gene polymorphism is associated with attention deficit hyperactivity disorder.

@article{Lahoste1996DopamineDR,
  title={Dopamine D4 receptor gene polymorphism is associated with attention deficit hyperactivity disorder.},
  author={Gerald J Lahoste and James M. Swanson and Sharon B. Wigal and Charles G. Glabe and Tim L. Wigal and Nicole King and James L Kennedy},
  journal={Molecular psychiatry},
  year={1996},
  volume={1 2},
  pages={121-4}
}
Dopamine is believed to play a major role in the manifestation of attention deficit hyperactivity disorder (ADHD), which affects 3-6% of school-age children and shows evidence of familiarity. The dopamine D4 receptor, which is preferentially distributed in cortical and limbic regions of the brain, is currently of major interest because of the high degree of functionally relevant variability in its gene (DRD4), and the association of this gene with Novelty Seeking behavior. We examined the… CONTINUE READING
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