Dopamine D4 receptor gene and personality dimensions in Brazilian male alcoholics.

@article{Bau1999DopamineDR,
  title={Dopamine D4 receptor gene and personality dimensions in Brazilian male alcoholics.},
  author={Claiton Henrique Dotto Bau and Tatiana Roman and Silvana Almeida and Mara H Hutz},
  journal={Psychiatric genetics},
  year={1999},
  volume={9 3},
  pages={139-43}
}
The presence of the seven-repeat allele of the VNTR in the exon 3 of the dopamine D4 receptor gene (DRD4) has been associated in healthy subjects to the personality trait of novelty seeking. The present study focuses these observations on a sample of Brazilian male alcoholics, evaluated on the temperament dimensions originally described by Cloninger. The genotypes observed are in agreement with those expected under Hardy-Weinberg equilibrium. Subjects with the seven-repeat allele manifest lower… CONTINUE READING
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