Dopamine D4 receptor antagonist L745,870 abolishes cognitive effects of intracerebroventricular angiotensin IV and des-Phe(6)-Ang IV in rats.

Abstract

In this study effect of L745,870, a selective D(4) dopamine (DA) receptor blocker, on the pro-cognitive action of intracerebroventricularly (icv) injected angiotensin IV (Ang IV) and des-Phe(6)-Ang IV was examined. Male Wistar rats weighing 180-200 g were used. Both peptides given at the dose of 1 nmol facilitated recall of a passive avoidance (PA… (More)
DOI: 10.1016/j.euroneuro.2008.08.011

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@article{Braszko2009DopamineDR, title={Dopamine D4 receptor antagonist L745,870 abolishes cognitive effects of intracerebroventricular angiotensin IV and des-Phe(6)-Ang IV in rats.}, author={Jan J{\'o}zef Braszko}, journal={European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology}, year={2009}, volume={19 2}, pages={85-91} }