Dopamine D3 receptor antagonists improve the learning performance in memory-impaired rats

@article{Laszy2004DopamineDR,
  title={Dopamine D3 receptor antagonists improve the learning performance in memory-impaired rats},
  author={Judit Laszy and Istv{\'a}n Laszlovszky and Istv{\'a}n Gyerty{\'a}n},
  journal={Psychopharmacology},
  year={2004},
  volume={179},
  pages={567-575}
}
RationaleThe dopamine D3 receptor has been extensively studied in animal models of drug abuse and psychosis; however, less is known on its possible role in cognitive functions.ObjectivesThis study investigated the effects of different D3 antagonists and a partial agonist on spatial learning performance in a water labyrinth test.MethodsRats had to swim through a labyrinth system by making correct directional turns at three choice-points. The number of errors was recorded in three daily trials… 

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