Dopamine D1 receptor and protein kinase C isoforms in spontaneously hypertensive rats.

@article{Yao1998DopamineDR,
  title={Dopamine D1 receptor and protein kinase C isoforms in spontaneously hypertensive rats.},
  author={L P Yao and Xiao Xi Li and P Y Yu and Jing Li Xu and Laureano D. Asico and Pedro A. Jos{\'e}},
  journal={Hypertension},
  year={1998},
  volume={32 6},
  pages={1049-53}
}
-Dopamine, via D1-like receptors, stimulates the activity of both protein kinase A (PKA) and protein kinase C (PKC), which results in inhibition of renal sodium transport. Since D1-like receptors differentially regulate sodium transport in normotensive and hypertensive rats, they may also differentially regulate PKC expression in these rat strains. Thus, 2 different D1-like agonists (fenoldopam or SKF 38393) were infused into the renal artery of anesthetized normotensive Wistar-Kyoto rats (WKY… CONTINUE READING
16 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 16 extracted citations

Similar Papers

Loading similar papers…