Dopamine D<ce:inf loc=post>2</ce:inf> receptor binding before and after treatment of major depression measured by [<ce:sup loc=pre>123</ce:sup>I]IBZM SPECT

@article{Klimke1999DopamineDL,
  title={Dopamine D<ce:inf loc=post>2</ce:inf> receptor binding before and after treatment of major depression measured by [<ce:sup loc=pre>123</ce:sup>I]IBZM SPECT},
  author={Ansgar Klimke and Rolf Larisch and A Janz and Henning Vosberg and Wolfgang Gaebel},
  journal={Psychiatry Research: Neuroimaging},
  year={1999},
  volume={90},
  pages={91-101}
}
Fifteen patients fulfilling DSM-IV criteria for major depression were investigated with the specific dopamine D2 w123 x Ž . Ž . receptor antagonist I iodobenzamide IBZM . Two single photon emission computed tomography SPECT examinations were performed before and after 6 weeks of treatment with a selective serotonin re-uptake inhibitor Ž . SSRI . Striatal D receptor binding was calculated and normalized to the cerebellum. In a non-psychiatric control 2 Ž . w123 x group ns17 , which was… CONTINUE READING

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