Dopamine Antagonism Decreases Willingness to Expend Physical, But Not Cognitive, Effort: A Comparison of Two Rodent Cost/Benefit Decision-Making Tasks

@article{Hosking2015DopamineAD,
  title={Dopamine Antagonism Decreases Willingness to Expend Physical, But Not Cognitive, Effort: A Comparison of Two Rodent Cost/Benefit Decision-Making Tasks},
  author={Jay G. Hosking and Stan B Floresco and Catharine A. Winstanley},
  journal={Neuropsychopharmacology},
  year={2015},
  volume={40},
  pages={1005-1015}
}
Successful decision making often requires weighing a given option’s costs against its associated benefits, an ability that appears perturbed in virtually every severe mental illness. Animal models of such cost/benefit decision making overwhelmingly implicate mesolimbic dopamine in our willingness to exert effort for a larger reward. Until recently, however, animal models have invariably manipulated the degree of physical effort, whereas human studies of effort have primarily relied on cognitive… CONTINUE READING
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