Dopamine 2 (DA-2) receptor assays using sympathetic nerve terminals.

  • J. P. Long
  • Published 2001 in Current protocols in pharmacology

Abstract

In vitro experiments using isolated atria with and without superfusion can be used to quantify the dopamine-2 (DA-2) receptor stimulating activity of compounds. This receptor mechanism decreases the amount of norepinephrine released from sympathetic nerve terminals by neuronal impulses. DA-2 receptor agonists (stimulants) are very active and induce several… (More)
DOI: 10.1002/0471141755.ph0414s06

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