Dopamine: Functions, Signaling, and Association with Neurological Diseases

  title={Dopamine: Functions, Signaling, and Association with Neurological Diseases},
  author={Marianne O. Klein and Daniella S. Battagello and Ariel R Cardoso and David N Hauser and Jackson Cioni Bittencourt and Ricardo G. Correa},
  journal={Cellular and Molecular Neurobiology},
The dopaminergic system plays important roles in neuromodulation, such as motor control, motivation, reward, cognitive function, maternal, and reproductive behaviors. Dopamine is a neurotransmitter, synthesized in both central nervous system and the periphery, that exerts its actions upon binding to G protein-coupled receptors. Dopamine receptors are widely expressed in the body and function in both the peripheral and the central nervous systems. Dopaminergic signaling pathways are crucial to… 
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