Dopa-responsive dystonia -- the story so far.

  title={Dopa-responsive dystonia -- the story so far.},
  author={Oliver Bandmann and Nicholas Wood},
  volume={33 1},
Dopa-responsive dystonia (DRD) is an eminently treatable condition and its recognition is therefore of crucial importance. In classical cases, the disease manifests in early childhood with walking problems due to dystonia of the lower limbs. The dystonia is frequently accompanied by "parkinsonian" features such as reduced facial expression or slowing of fine finger movements. Biochemically, the disorder is typically characterized by low levels of the neurotransmitter metabolite homovanillic… CONTINUE READING