Donor tissue-specific exosome profiling enables noninvasive monitoring of acute rejection in mouse allogeneic heart transplantation.

@article{Habertheuer2018DonorTE,
  title={Donor tissue-specific exosome profiling enables noninvasive monitoring of acute rejection in mouse allogeneic heart transplantation.},
  author={Andreas Habertheuer and Laxminarayana Korutla and Susan Y. Rostami and Sanjana Reddy and Priti Lal and Ali Naji and Prashanth Vallabhajosyula},
  journal={The Journal of thoracic and cardiovascular surgery},
  year={2018},
  volume={155 6},
  pages={2479-2489}
}
OBJECTIVE In heart transplantation, there is a critical need for development of biomarkers to noninvasively monitor cardiac allografts for immunologic rejection or injury. Exosomes are tissue-specific nanovesicles released into circulation by many cell types. Their profiles are dynamic, reflecting conditional changes imposed on their tissue counterparts. We… CONTINUE READING