Donor selection for unrelated cord blood transplants.

@article{Gluckman2006DonorSF,
  title={Donor selection for unrelated cord blood transplants.},
  author={Eliane Gluckman and Vanderson Rocha},
  journal={Current opinion in immunology},
  year={2006},
  volume={18 5},
  pages={565-70}
}
The number of unrelated cord blood transplants is increasing, with more than 8000 patients reported worldwide. Criteria of donor choice have been identified. Cell dose measured by number of nucleated cells is the most important factor, thus increases in cell dose can partially overcome the presence of HLA incompatibilities. Overall, increasing the number of HLA incompatibilities is associated with non-engraftment, but it also decreases the risk of relapse in patients with malignant disease… CONTINUE READING

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