Donor selection for natural killer cell receptor genes leads to superior survival after unrelated transplantation for acute myelogenous leukemia.

@article{Cooley2010DonorSF,
  title={Donor selection for natural killer cell receptor genes leads to superior survival after unrelated transplantation for acute myelogenous leukemia.},
  author={Sarah Cooley and Daniel J. Weisdorf and Lisbeth A. Guethlein and John P. Klein and Tao Wang and Chap T. Le and Steven G. E. Marsh and Daniel E. Geraghty and Stephen R. Spellman and Michael D. Haagenson and M. Damon Ladner and E. A. Trachtenberg and Peter Parham and Jeffrey S Miller},
  journal={Blood},
  year={2010},
  volume={116 14},
  pages={2411-9}
}
Killer-cell immunoglobulin-like receptor (KIR) genes form a diverse, immunogenetic system. Group A and B KIR haplotypes have distinctive centromeric (Cen) and telomeric (Tel) gene-content motifs. Aiming to develop a donor selection strategy to improve transplant outcome, we compared the contribution of these motifs to the clinical benefit conferred by B haplotype donors. We KIR genotyped donors from 1409 unrelated transplants for acute myelogenous leukemia (AML; n = 1086) and acute… CONTINUE READING
Highly Influential
This paper has highly influenced 17 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 220 extracted citations

Comment: Shall Killer Cell Immunoglobulin-Like Receptor Genotyping be Incorporated in Donor Search Algorithms?

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation • 2016
View 4 Excerpts
Highly Influenced

References

Publications referenced by this paper.
Showing 1-10 of 53 references

Similar Papers

Loading similar papers…