Donor lymphocyte infusions for relapse after allogeneic transplantation: when, if and for whom?

@article{Chang2013DonorLI,
  title={Donor lymphocyte infusions for relapse after allogeneic transplantation: when, if and for whom?},
  author={Yingjun Chang and Xiaojun Huang},
  journal={Blood reviews},
  year={2013},
  volume={27 1},
  pages={55-62}
}
Donor lymphocyte infusion (DLI) using unstimulated leukapheresis is one of the most effective treatment strategies for patients with hematological malignancies; its graft-versus-leukemia effects make it especially effective in chronic myeloid leukemia patients who relapsed after allogeneic stem cell transplantation (allo-HSCT). However, DLI application is limited by the development of graft-versus-host disease and aplasia, and thus cannot be routinely applied for prophylaxis. Therefore… CONTINUE READING
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