Donor age and long-term culture affect differentiation and proliferation of human bone marrow mesenchymal stem cells

Abstract

Bone marrow-derived human mesenchymal stem cells (BM-hMSCs) represent a promising cell-based therapy for a number of degenerative conditions. Many applications require cell expansion and involve the treatment of diseases and conditions found in an aging population. Therefore, the effects of donor age and long-term passage must be clarified. In this study… (More)
DOI: 10.1007/s00277-012-1438-x

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Cite this paper

@article{Zaim2012DonorAA, title={Donor age and long-term culture affect differentiation and proliferation of human bone marrow mesenchymal stem cells}, author={Merve Zaim and Serap Karaman and Guven Cetin and Sevim Isik}, journal={Annals of Hematology}, year={2012}, volume={91}, pages={1175-1186} }