Donepezil across the spectrum of Alzheimer's disease: dose optimization and clinical relevance.

@article{Lee2015DonepezilAT,
  title={Donepezil across the spectrum of Alzheimer's disease: dose optimization and clinical relevance.},
  author={Jeong-hoon Lee and S-K Jeong and Byeong C. Kim and Ki Won Park and Amitabh Dash},
  journal={Acta neurologica Scandinavica},
  year={2015},
  volume={131 5},
  pages={259-67}
}
Alzheimer's disease (AD) is an irreversible and progressive neurodegenerative disorder. AD is the most common cause of dementia worldwide, and its incidence is increasing in line with population aging. The primary feature of AD is progressive cognitive decline, and severe AD is characterized by reduced communication skills and mobility. However, successful treatment can substantially improve quality of life. Donepezil is an acetylcholinesterase inhibitor approved for use across the full… CONTINUE READING