Domperidone in defective and insufficient lactation.

  title={Domperidone in defective and insufficient lactation.},
  author={Felice Petraglia and Lucia Catucci and Silvia Sardelli and M L Pieroni and N D'Antona and Andrea Riccardo Genazzani},
  journal={European journal of obstetrics, gynecology, and reproductive biology},
  volume={19 5},
The clinical use of anti-dopaminergic drugs to stimulate plasma PRL levels, to induce lactogenesis and maintain an adequate lactation has been widely suggested, taking into consideration the main inhibitory role of hypothalamic dopamine on PRL secretion. We therefore studied the effects of domperidone (DOM), a direct anti-dopaminergic drug with a low tendency to be secreted in the milk and which does not cross the blood-brain barrier, on inducing lactogenesis in 8 puerperal women with a history… CONTINUE READING


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